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Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...
Published: 1/29/2018
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Inventor(s): Robert Pagels, Robert Prud'homme, Chester Markwalter
Keywords(s): Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Repair Mutants
Princeton Docket # 15-3160
Researchers in the Department of Molecular Biology at Princeton University have identified drug resistance mutations in key pathways in chemoresistance using the mutator phenotype of mismatch repair defective Saccharomyces cerevisiae cells and...
Published: 2/28/2018
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Inventor(s): Alison Gammie, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, life science research tools, model organism, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Synthetic Lethal Targeting of Mismatch Repair Defective Cells for Cancer Treatment
Princeton Docket # 15-3159
Researchers in the Department of Molecular Biology at Princeton University have developed a yeast-based high throughput chemical synthetic lethality screen to identify clinically relevant small molecules. Its application has led to the discovery...
Published: 2/28/2018
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Inventor(s): Alison Gammie, Hahn Kim, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Dual Base Metal Catalysis for Alkene and Hydrogen Production via Acceptorless and Selective Dehydrogenation of Alkanes
Princeton Docket # 15-3117
Researchers in the Department of Chemistry at Princeton University have developed a new catalyst combination, comprising of a tungsten-based polyoxometalate and cobaloxime, in order to dehydrogenate alkanes...
Published: 3/15/2018
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Inventor(s): Erik Sorensen, Julian West
Keywords(s): catalyst, Chemistry, organic synthesis, petrochemical, research tool
Category(s): Chemistry
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Transition Metal Catalysts for Olefin Polymerization
Princeton Docket # 14-3038
Presently, only free radical copolymerizations of ethylene and polar industrial monomers (e.g, vinyl acetate or acrylic acid) at high temperatures and very high pressures have been commercialized. This existing technology, however, inherently lacks precise control over...
Published: 3/15/2018
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Inventor(s): Brad Carrow, Wei Zhang
Keywords(s): catalyst, Chemistry, polymer chemistry
Category(s): Chemistry
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Quantum Dot Micromaser
Docket # 14-3032
Solid-state superconducting circuits are versatile systems in which quantum states can be engineered and controlled. Recent progress in this area has opened up exciting possibilities for exploring fundamental physics as well as applications in quantum information technology. In a series of experiments it was shown...
Published: 3/15/2018
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Inventor(s): Jason Petta, Yinyu Liu
Keywords(s): Chemistry, semiconductor
Category(s): Opto-Electronics/ Electrical Engineering
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Princeton Docket # 14-3027Elevated levels of fluoride in groundwaters of granitic and basaltic terrains pose a major environmental problem and are affecting millions of people all over the world. Everyday many people, especially in the developing world, are exposed to elevated levels of fluoride, which has been found to be well above the World Health...
Published: 3/15/2018
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Inventor(s): Satish Myneni, Peter Jaffe
Keywords(s): Chemistry, civil engineering, earth science, green tech, polymer chemistry, wastewater management, water
Category(s): Ceramics/Material Sciences
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Metal@Polymer Nanoparticles by Simultaneous Precipitation
and Reduction
Princeton Docket #14-3014
Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Robert Prud'homme, Rui Liu, Chris Sosa
Keywords(s): catalyst, Chemistry, drug delivery, energy, Imaging, nanotechnology
Category(s): Chemistry
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Yolk-Shell Nanostructures via One-Step Core-Shell-Shell Template
Princeton Docket #14-2983
Yolk-shell nanoparticles are characterized by a movable core encapsulated inside a polymer or inorganic shell. At present, only a few ingenious routes for the generation of yolk-shell nanoparticles exist. These methods require cumbersome synthesis, multi-step...
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Rui Liu
Keywords(s): catalyst, Chemistry, drug delivery
Category(s): Chemistry
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Polymer Janus Nanoparticles By Flash NanoPrecipitation
Princeton Docket # 14-2981
Janus particles are characterized by two physically distinct regions within or on the surface of the particle. Polymer Janus nanoparticles, in particular, contain at least two different polymer regions. At present, only a few ingenious routes for the generation of...
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Robert Prud'homme, Chris Sosa
Keywords(s): biomarker/diagnostic, Biotechnology/Pharmaceuticals, catalyst, Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Chemistry
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