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Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...
Published: 1/29/2018
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Inventor(s): Robert Pagels, Robert Prud'homme, Chester Markwalter
Keywords(s): Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Princeton Docket # 16-3183-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a nanocarrier based approach to enable and enhance adjunctive therapies for microbial infections by simultaneous encapsulation and delivery of all components.Microbial infections have become increasingly difficult to...
Published: 3/24/2022
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Inventor(s): Robert Prud'homme, Hoang Lu
Keywords(s): anitbiotics, drug delivery, Imaging, nanotechnology
Category(s): Biotechnology/Pharmaceuticals
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Princeton Docket # 16-3177-1Researchers in the Department of Mechanical and Aerospace Engineering at Princeton University have proposed a method to control the opening and closing of mechanosensitive (MS) channels on a cell membrane.MS channels are membrane proteins that can be gated by membrane tension, and they play major roles in mechano-sensation...
Published: 3/6/2018
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Inventor(s): Howard Stone, YuaN-Nan Young, Shravan Veerapaneni, On Shun Pak, Gary Marple
Keywords(s): drug delivery, fluid mechanics
Category(s): Civil/Environmental Engineering
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Princeton Docket # 15-3172-1Researchers in the Department of Mechanical and Aerospace Engineering at Princeton University have developed a method to produce large unilamellar lipid vesicles with controlled size.Fusion between suspended lipid vesicles is difficult to achieve without membrane proteins or ions, because the vesicles have extremely low equilibrium...
Published: 2/28/2018
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Inventor(s): Sangwoo Shin, Jesse Ault, Howard Stone
Keywords(s): drug delivery, fluid mechanics
Category(s): Mechanical, Civil/Environmental Engineering
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Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...
Published: 1/29/2018
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Inventor(s): Nikolas Weissmueller, Robert Prud'homme, Ruth Rosenthal
Keywords(s): anti-infectives, drug delivery, nanotechnology, vaccines
Category(s): Biotechnology/Pharmaceuticals
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Metal@Polymer Nanoparticles by Simultaneous Precipitation
and Reduction
Princeton Docket #14-3014
Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Robert Prud'homme, Rui Liu, Chris Sosa
Keywords(s): catalyst, Chemistry, drug delivery, energy, Imaging, nanotechnology
Category(s): Chemistry
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Microfluidic Method for Continuous Production of Microfibers with Embedded Droplets
Princeton Docket #14-2982
Fibers are a useful medium for numerous applications, including drug delivery. Current technologies usually make fibers of homogeneous chemical composition or employ axial core-shell structures. To create more complex shapes and compositions,...
Published: 3/15/2018
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Inventor(s): Howard Stone, Janine Nunes, Eujin Um, Tamara Pico
Keywords(s): drug delivery, life science research tools, regenerative medicine, research tool, soft scaffolds, therapeutic, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics
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Yolk-Shell Nanostructures via One-Step Core-Shell-Shell Template
Princeton Docket #14-2983
Yolk-shell nanoparticles are characterized by a movable core encapsulated inside a polymer or inorganic shell. At present, only a few ingenious routes for the generation of yolk-shell nanoparticles exist. These methods require cumbersome synthesis, multi-step...
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Rui Liu
Keywords(s): catalyst, Chemistry, drug delivery
Category(s): Chemistry
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Polymer Janus Nanoparticles By Flash NanoPrecipitation
Princeton Docket # 14-2981
Janus particles are characterized by two physically distinct regions within or on the surface of the particle. Polymer Janus nanoparticles, in particular, contain at least two different polymer regions. At present, only a few ingenious routes for the generation of...
Published: 3/15/2018
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Inventor(s): Rodney Priestley, Robert Prud'homme, Chris Sosa
Keywords(s): biomarker/diagnostic, Biotechnology/Pharmaceuticals, catalyst, Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Chemistry
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A Novel and Low-Cost Method for Nano-emulsion Preparation
Princeton Docket # 13-2871-1
Nano-emulsions are used in novel multiphase materials for home and personal care products, drug-delivery applications, structured liquids, etc. However, current methods for the preparation of nano-emulsions require either high-energy methods or sophisticated devices....
Published: 3/15/2018
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Inventor(s): Luben Arnaudov, Simeon Stoyanov, Howard Stone, Jie Feng, Matthieu Roché, Daniele Vigolo
Keywords(s): Chemistry, drug delivery, materials
Category(s): Ceramics/Material Sciences, Chemistry, Biotechnology/Pharmaceuticals
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