Search Results - tom+muir

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Trackable Quorum-Sensing Molecules for Diagnostic Applications Princeton Docket # 17-3325-1High quality medical imaging technology has been one of most important developments in clinical care and personalized medicine. Pinpointing the source and cause of disease in a patient allows targeted and optimal treatment, saving time and money. Applying this type of imaging accuracy to the identification of bacterial pathogens... Published: 3/25/2022   |   Inventor(s): Bonnie Bassler, Howard Stone, Min Kim, Aishan Zhao, Tom Muir Keywords(s):   Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Inhibiting Quorum Sensing of Bacteria in Healthcare and Industrial Devices Through Conjugation of Anti-Quorum Sensing Molecules to Surfaces A surface-coating approach for bacteria-free health-care and industrial devices Docket # 15-3136 Bacteria frequently act as members of collectives to create surface-attached communities called biofilms and to synchronously activate the production of virulence factors. Bacterial group behaviors are regulated by a cell-cell communication process called... Published: 2/5/2018   |   Inventor(s): Min Kim, Aishan Zhao, Howard Stone, Bonnie Bassler, Tom Muir Keywords(s):   Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets Princeton Docket # 14-2972 Researchers in the Department of Chemistry at Princeton University have developed the first phosphohistidine (pHis)-specific antibody, which has enabled the selective detection and identification of pHis... Published: 3/15/2018   |   Inventor(s): Tom Muir, Rob Oslund, JunG-Min Kee Keywords(s): antibody, biomarker/diagnostic, Biotechnology/Pharmaceuticals, Chemistry, drug discovery, drug target, life science research tools, posttranslational modification, protein engineering, protein phosphorylation, therapeutic Category(s): Biotechnology/Pharmaceuticals, Chemistry

DNA Barcoding of Designer Mononucleosome and Chromatin Array Libraries for the Profiling of Chromatin Readers, Writers, Erasers, and Modulators Thereof Chromatin Biochemistry Using Barcoded Nucleosome Libraries: A Versatile Platform to Screen and Identify Epigenetic Signaling Pathways and Drug Targets Princeton Docket # 12-2822 Researchers at Princeton University have developed a biochemical strategy to decipher chromatin signaling based on the streamlined preparation of DNA-barcoded nucleosome... Published: 3/15/2018   |   Inventor(s): Tom Muir, Thi Thanh Uyen Nguyen, Manuel Muller Keywords(s):   Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics