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Princeton Docket # 14-3007
Researchers in the Department of Molecular Biology at Princeton University have isolated a mutant strain of Escherichia coli that is specifically more resistant to vancomycin than is its wild-type parent. The resistance mutation in this strain alters an enzyme normally involved in LPS biosynthesis causing it to synthesize...
Published: 3/15/2018
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Inventor(s): Thomas Silhavy, Marcin Grabowicz, Daniel Kahne, Matthew Lebar, Dorothee Andres
Keywords(s): anitbiotics, antibody, immunology, therapeutic, vaccines
Category(s): Biotechnology/Pharmaceuticals
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Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets
Princeton Docket # 14-2972
Researchers in the Department of Chemistry at Princeton University have developed the first phosphohistidine (pHis)-specific antibody, which has enabled the selective detection and identification of pHis...
Published: 3/15/2018
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Inventor(s): Tom Muir, Rob Oslund, JunG-Min Kee
Keywords(s): antibody, biomarker/diagnostic, Biotechnology/Pharmaceuticals, Chemistry, drug discovery, drug target, life science research tools, posttranslational modification, protein engineering, protein phosphorylation, therapeutic
Category(s): Biotechnology/Pharmaceuticals, Chemistry
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Princeton University Invention #
09-2509
The involvement of the EGFR signaling pathway in bone metastasis has been
implicated by a number of studies. However, the therapeutic significance by
targeting EGFR signaling in the tumor-stroma interface has not been evaluated.
Researchers in the Molecular Biology Department at Princeton...
Published: 3/15/2018
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Inventor(s): Yibin Kang, Xin Lu
Keywords(s): antibody, cancer/oncology, therapeutic
Category(s): Biotechnology/Pharmaceuticals
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