Method for Loading Macro-Molecules onto Micro/Nano Fluidic Devices from Gel Plugs

            Researchers at Princeton University have developed an improved method for loading macro-molecules, subject to shearing, such as genomic DNA, from gel plugs into micro or nanofluidic devices.  Current methods using electroelution for extraction of DNA from agarose gel plugs are extremely time-consuming due to the weak electrical fields developed in the loading well.  This new method enables stronger electric fields that permit unloading as well as decreased loading times.   This method provides a world/chip interface where large biomolecules can be loaded onto and unloaded from micro/nanofluidic devices efficiently, and without shearing of the molecules. 

Princeton is currently seeking industrial collaborators to commercialize this technology.   Patent protection is pending.

            For more information please contact:

                        William H. Gowen

                        Office of Technology Licensing and Intellectual Property

                        Princeton University

                        4 New South Building

                        Princeton, NJ 08544-0036

                        (609) 258-6762

                        (609) 258-1159 fax

                        wgowen@princeton.edu