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Antibacterial Adjuvants for Reduced Cationic Antimicrobial Peptide Dosing and Combination TherapyPrinceton Docket # 20-3616-1 Researchers in the Department of Chemistry at Princeton University and the Department of Chemistry at San Jose State University have discovered compounds which increase the susceptibility of both CAP-resistant as well...
Published: 3/22/2022
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Inventor(s): Laura Conrad, Martin Semmelhack, Zinan Zhang, Minh Tran, Lauren Blankenship
Keywords(s): anitbiotics
Category(s): Biotechnology/Pharmaceuticals
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X-Ray Assisted Electron Microscopy Staining ProcedurePrinceton Docket # 19-3530Researchers in the Princeton Neuroscience Institute, Princeton University have developed an X-ray assisted staining procedure, which allows for tight control over the staining process and can serve as a very important and unique entry point for staining quality control while...
Published: 3/3/2022
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Inventor(s): Adrian Wanner, David Tank, Sebastian Seung
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Docket # 17-3362Although considerable progress has been made in understanding the genetic basis of morphologic traits (e.g. body size, coat color) in dogs and wolves, the genetic basis of their behavioral divergence is poorly understood. Researchers at Princeton University have conducted a genome-wide SNP study and identified genomic regions under positive...
Published: 3/1/2022
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Inventor(s): Bridgett vonHoldt, Monique Udell, Janet Sinsheimer
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Princeton Docket # 17-3325-1High quality medical imaging technology has been one of most important developments in clinical care and personalized medicine. Pinpointing the source and cause of disease in a patient allows targeted and optimal treatment, saving time and money. Applying this type of imaging accuracy to the identification of bacterial pathogens...
Published: 3/25/2022
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Inventor(s): Bonnie Bassler, Howard Stone, Min Kim, Aishan Zhao, Tom Muir
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Princeton Docket # 18-3374-1The first and only method for preparing high-valued aliphatic isocyanates via direct C-H activation has been developed by researchers at Princeton University. Organic isocyanates are versatile intermediates that provide access to a wide range of functionalities found in pharmaceuticals and agrochemicals. This method harnesses...
Published: 2/5/2018
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Inventor(s): John Groves, Xiongyi Huang, Thompson Zhuang
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals, Chemistry
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Princeton Docket # 17-3323-1Princeton researchers have engineered a light emitting reporter to measure the real-time buildup of 2’-5’ linked oligoadenylates (2-5As) biochemically and in live cells using a one-step, high-throughput method.2-5As are produced in stressed human cells that accumulate double stranded RNA (dsRNA). 2-5A serves as...
Published: 3/2/2018
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Inventor(s): Alexei Korennykh, Alisha Chitrakar, Jesse Donovan
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Princeton Docket # 16-3268Chromatin immunoprecipitation (ChIP) is an affinity assay for detecting the interaction between a particular protein and DNA in cells. Using a protein-specific antibody, DNA bound by that protein can be isolated and identified using high throughput sequencing (ChIP-seq). One desirable way to prepare a DNA library for sequencing...
Published: 3/1/2018
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Inventor(s): Michael Levine, Kai Chen
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Light Activating Genetic Tools for Rapid and Reversible Clustering of Proteins In Vivo ` Princeton Docket # 16-3266-1, 17-3279-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed two novel molecular tools for rapid and reversible clustering...
Published: 1/29/2018
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Inventor(s): Clifford Brangwynne, Jared Toettcher, Yongdae Shin
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Princeton Docket # 16-3253-1Researchers in the Department of Molecular Biology, Princeton University have identified an innovative qPCR-based method for accurate and specific detection of immune marker RNAs generated by the action of double-stranded RNA (dsRNA) and RNase L. These markers provide one-of-a kind diagnostic tools for the dsRNA response...
Published: 1/29/2018
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Inventor(s): Alexei Korennykh, Jesse Donovan
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Princeton Docket # 16-3239-1Researchers in the Department of Molecular Biology at Princeton University have developed an innovative therapy for the treatment of bacterial infections. The invention combines two unique discoveries to generate a novel, safe approach to combat bacterial infections without generating resistance. The first discovery is small...
Published: 1/29/2018
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Inventor(s): Nina HoylanD-Kroghsbo, Jon Paczkowski, Bonnie Bassler
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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