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A Novel Assay for Sirtuin 4 (SIRT4) Lipoamidase Activity and the Activity of the Pyruvate Dehydrogenase Complex
Princeton Docket # 14-3002
A novel assay for measuring the lipoamidase activity of SIRT4 in mammalian cells and tissue samples has been created. A procedure by which the lipoamide cofactor activity can be monitored in mammalian cells has...
Published: 3/15/2018
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Inventor(s): Thomas Shenk, Todd Greco, Ileana Cristea, Rommel Mathias, Adam Oberstein
Keywords(s): biologics, Biotechnology/Pharmaceuticals, genomics/proteomics (software), virology
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Princeton University Invention # 07-2381
Researchers in the Molecular Biology department at Princeton University
and the Simons Center for Systems Biology at the Institute for Advanced Study
have developed an improved algorithm for the prediction of mRNAs that are
targeted by known microRNAs. The algorithm was employed to identify...
Published: 3/15/2018
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Inventor(s): Thomas Shenk, Arnold Levine, Jiri Vanicek, Eain Murphy, Harlan Robins
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Princeton University Invention #
90-0954
The technology
as described in US patent # 5,753,500 relates to a method for producing
substantially pure stocks of recombinant adeno-associated virus, free of the
adeno-associated helper virus found associated with previously available
recombinant AAV. These pure stocks can be used to introduce exogenous...
Published: 3/15/2018
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Inventor(s): Mark Labow, Stephan Baim, Arnold Levine, Thomas Shenk
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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